Tuesday, August 25, 2020

Pacing Essay Example | Topics and Well Written Essays - 750 words

Pacing - Essay Example Furthermore, the paper will cover learning for troublesome subjects in English language learners’ class. Pacing Introduction According to Alan Hofmeister and Margaret Libke, pacing involves both educational plan and exercise pacing. A pacing guide is a composed timetable that contains the ideas, themes and aptitudes that are connected the educational plan to be secured inside a predetermined timeframe (Richards and Lockhart, 2006, p 126). Educational program pacing is worried about the rate at which progress is made in conveying the educational plan while exercise pacing is worried about the rate at which an educator leads the individual exercises. From past examination, it is apparent that low-accomplishing understudies adapt adequately when exercises are led at lively pace since increasingly content is canvassed in study hall (Hofmeister and Lubke, 1999, p 19). In any case, it is expected that the exercise trouble will allow the students to accomplish a higher pace of achiev ement since profoundly troublesome exercises or substance can't very much learned at instructional pace. Great pacing gives the understudies the correct cadence of the exercise and makes an observation that the exercise is advancing at the correct speed (Richards and Lockhart, 2006, p 127). Exercise pacing is basic in study hall learning. Exercise pacing acts a marker that understudies use to measure the speed and progress of learning in a specific exercise. As needs be, pacing empowers the educators or instructors to adjust the technique for instructing to the destinations of learning and level of trouble of the exercise (Richards and Lockhart, 2006, p 131). Viable pacing empowers the instructor to hold the consideration of the understudies in this manner adding to powerful accomplishment of the learning destinations in a specific exercise. In such manner, understudies have earlier view of the measure of substance that will be secured inside a specific period in this way empowering them to think during the whole exercise time frame (Hofmeister and Lubke, 1999, p 27). Exercise pacing helps in progressing starting with one learning subject then onto the next during the exercise. In such manner, pacing guarantees that instructors convey information in a sound and consecutive way since no interferences, for example, missing instructional materials happen. Exercise pacing stirs learning interest and controls students’ social issues during the exercise. Exercise pacing encourages commitment from the students through requesting explanations, quality addressing and inclusion of adequate substance inside the exercise time frame (Richards and Lockhart, 2006, p 132). Pacing for a class that incorporates English Language Learner (ELL) understudies and for a class that does exclude ELL understudies will vary essentially. For ELL class, clarification of specific vocabularies and key terms is fundamental before showing the understudies new ideas (Hofmeister and Lubke , 1999, p 52). For English Language Learners (ELL), the educator must move at a more slow pace while showing the ideas through non-verbal communication so as to keep up the consideration of the students. For ELL understudies, the instructor must present learning materials and directions outwardly through giving gifts and not depending altogether on oral guidelines (Richards and Lockhart, 2006, p 139). The pacing must encourage language dominance through away from of exercise destinations and meaning of the language targets. The exercise content must be lined up with English language capability and exercise exercises must incorporate exercise ideas with English language practice openings, for example, composing sonnets (Hofmeister and Lub

Saturday, August 22, 2020

Operations Management The increasing amount of Mass Customization in Essay

Activities Management The expanding measure of Mass Customization in the Automobile business - Essay Example Around then, most would agree that purchasers were increasingly inspired by the capacity of the item, and on account of Henry Ford, his market mastery kept different makers from offering personalization as an extraordinary selling point. Nonetheless, as cars turned out to be increasingly reasonable, shoppers started to look for ways with which they could alter their assets with a view separating themselves from different customers, and to make their own feeling of personality. The developing need to set up this character prompted the progressive customization in the vehicle business where cars could be created to coordinate individual customer needs (Mayland and Heiland 2005). Mass customization requires a lot of contribution from all providers and makers associated with the tasks the board procedure. Every one of these providers and makers will be a piece of different ventures too, which have their own innovative advances and business procedures. For mass customization to be effecti ve the vehicle business should take a gander at changing its provider connections, however in doing so needs to guarantee that its relationship isn't influence its providers relationship with makers. The vehicle business will in this manner need to embrace a couple of instances of good practice from the administration business, as mass customization has brought the customer into its procedures. Mass customization is probably going to make a system of providers and a gracefully bind that is remarkable to customary ones, yet this may likewise include receiving absolutely extreme business procedures to keep up the wasteful aspects. This may include shaping business collusions and associations that will empower the car business to working intimately with its providers by sharing more data and being engaged with arranging and guaging as a gathering, instead of separately List of chapters I. 1.0 History and Background of the Automobile business The vehicle business is one which has its underlying foundations in America following the large scale manufacturing of vehicles by Henry Ford in 1912 (Mozian et al 2007). The large scale manufacturing of autos has now become a worldwide marvel with different nations, for example, Germany, Brazil and Japan being key players in the business. Because of this worldwide arrive at the car business is encountering impacts which have constrained the business to re-evaluate the manner in which they work. For example, producers are having changing associations with their clients, as more interest significant levels of personalization; makers are shaping new organizations with providers so as to satisfy their client needs as far as quality and cost; and these two impacts have prompted the need to re-develop the production line floor to oblige the numbers and degrees of personalization requested by the client (Benko and McFarlane 2003). At the point when Henry Ford mass delivered the vehicle in 1912, he presented the idea of large scale manufacturing which made it workable for ventures to fabricate standard items in enormous amounts at low unit costs (Mayland and Heiland 2005). This implied the car business around then, could fabricate autos that were indistinguishable, and this was to a great extent conceivable because of buyer mentalities. Around then, any reasonable person would agree that purchasers

Friday, August 7, 2020

Google

Google With several of the core General Institute Requirements out of the way, sophomore year was really the dawn of my computer science life at MIT. Impostor syndrome started to take a backseat, and taking CS classes I enjoyed and did reasonably well in was a confidence booster. Soon enough though, I had to start thinking about internships, and I couldn’t help but feel the creeping approach of “not-enoughness. As career fair drew closer, resume workshops and interview tips began to dominate my inbox. Companies were hosting multitudes of events on campus, drawing us in with tech talks and lotteries for electronic swag, which we could usually enter by submitting a resume. I didn’t have a resume, and when I solicited some sample resumes from my friends, a clear difference emerged. On theirs: Github repositories populated with a multitude of extracurricular code, polished websites, sophisticated projects. On mine: a spatter of somewhat relevant classes and side projects I felt were too simple to be worth including. After speaking with some friends at Alpha Delta Phi, I consulted with staff at MIT’s Career Development office. Around the period of the fall Career Fair Week, the office let students book quick appointments for resume reviews, interview tips, offer negotiation tactics, and so on. I met with a nice lady who encouraged me to include my Olympiad and writing experiences from before MIT, as well as compensate for my relatively low CS experience by emphasizing one of the bigger projects I’d implemented in an MIT class. All of a sudden, I had something of a resume, but it still felt inadequate. Career Fair came and went in a blink. I stopped by for less than an hour and quickly left, after an enormous buildup of anxiety took over. I spent the days and weeks that followed caught in the usual MIT routine, and put an internship search on the backburner. It wasn’t necessarily feeling like I couldn’t land an internship. A combination of (to my ears) an adequate but relatively average resume, insufficient experience, fear of interviewing and the constant workload MIT unraveled each day put me in a state of complacency career-wise. Then one evening, I received an e-mail about a talk Google was having on campus. It was right after one of my classes, and I figured it couldn’t hurt to check it out, and at the very least, grab some free swag. ** Most of the swag had vanished when I arrived (although I did manage to grab a nice pair of socks) but I came just in time to hear one of the Google engineers speak about his route to the company, starting from his freshman year in college with virtually no experience. He spoke passionately, and after the talk was over, a small ball had knotted my chest, a familiar ball that meant I was on the verge of doing something potentially nerve-wracking. I got back to my dorm, and immediately filled out an application for Google’s Engineering Practicum Internship Program. It was designed for college freshmen and sophomores with little experience in Computer Science, and seemed like just the perfect thing I needed. Boosted by this, I sent out my resume to several other companies (which would result in several rejection e-mails) over the days that followed. A few weeks after I’d sent out my resume, I got contacted by a recruiter to set up two back-to-back phone interviews, each of them roughly an hour long. They constituted my first coding interviews, and as such, I was incredibly nervous. I remember the twenty minutes or so prior to the first call. I was in my room, spread across the bed, and playing some Taylor Swift music, trying to get into a state of calmness. Breathe in. Breathe out. The interviews had a straightforward structure: the interviewers, current Google engineers, would spend a minute or two talking about themselves or about you, but pretty quickly, they’d get into the meat of the hour. You were given one or more challenges, which you solved by thinking aloud and writing code on a shared Google Doc, each keystroke and backspace visible. The first interview went pretty great; the second felt like a trainwreck in which my brain just decided to turn to mush and forget everything I knew about coding. I ended up having to do a third interview, which went well. Shortly afterward, I was accepted into the program. ** I interned twice at Google, first in 2015 at their Los Angeles Office as an Engineering Practicum Intern, and again in 2016 at their Boston Office (right across the MIT campus) as a Software Engineering Intern. Although the former program had a greater deal of mentorship, both summers essentially consisted of working Monday through Friday reading and writing code. Spending the summer of 2015 in Los Angeles was magical. I left the perpetual variability of Boston’s weather and stepped into a wonderland of mid-seventies stability. The apartment hunt was quite frustratingalthough Google helped out a great deal by providing interns with a housing stipend and giving us access to a document detailing how previous interns had gone about looking for housing. I ended up sharing a two-bedroom apartment with three other Google interns. It was unfurnished, and our only furnishings that summer were a small carpet that looked rather comical on the floor of a large, empty living room and a set of chairs. I purchased an air mattress that had a funny way of deflating when I was deep in sleep, so that I’d always wake up to my face on the ground. However, splitting that apartment four-ways, combined with the stipend, made it very affordable. Plus, with us on the twelfth floor, we had a sweeping view of the Los Angeles skyline. Before starting off work in LA, I spent a week at the Google Headquarters in Mountain View, an incredibly large campus I could see myself still getting lost in even if I were there for years. Orientation Week was fast-paced and intense, as we were introduced to the company’s culture, code base, practices, guidelines and sweet, sweet food. Interns were represented across multitudes of schools and from all over the country. We wore brightly-colored Noogler hats and probably had this look of constant wonder on our face. That week invoked familiar images of being new to the United States and to MIT, that overwhelming sense of utter fascination, of getting lost in a sea of brilliant minds. Innovation was happening quietly, in buildings all around us, and even if we couldn’t see it right then, we could feel it. And for those summers, in our own ways, we could be part of it. ** The binoculars-shaped LA office was designed by Frank Gehry, the same architect behind MIT’s distinctively shaped Stata Center. Its uniqueness was a fitting metaphor for everything that followed; my traditional notions of what an office typically looked like were met with Google’s own imagination of a workspace, the sort of bright-eyed, in-the-clouds imagination that MIT got me familiar with. The designs were thematic, incorporating features of the office locations into its structure. The perks were incredibly enticing too. Across both offices: free massages, an onsite barber, cafes serving breakfast, lunch and dinner, a gym, a music room, a game room, a library, fire poles down which we could slide, rock-climbing walls, and on the list goes. I remember thinking how the heck anyone got work done. ** And the work itself was the heart of my internships at Google. After spending endless hours speeding through MIT’s roulette of classes and labs and problem sets, getting to translate that to an industrial setting was quite the experience. Google has defined the entirety of my CS industry experience, and is thus my only reference point, but going behind-the-scenes into the company’s codebase, for me, bordered more on Harry-Potter-style magic than on technicity. As an intern, I had access to the vast majority of the company’s internal codebase, to which I could now add. For both summers, the early weeks of the internship were defined by reading through heaps of code and extensive documentations (Googlers will often complain about the variable quality of their code documentation, but it’s largely thorough, perhaps intimidatingly so). I felt a bit lost both times, just by the sheer newness of everything, but as the internship progressed, familiarity took over. I got to learn new languages, and then learn Google’s version of those languages. I got to learn their process of code review (every line of code gets reviewed before being checked in), code rollback, style guides. I got to learn about strange, powerful technologies implemented by their engineers, tech that made researching and processing large amounts of data seamless. I got to see the magic of Computer Science at a wider scale than I had in the past. My Los Angeles internship was a great mix of research and coding. The description that follows is about as high-level as I can get, but hopefully it paints something of a picture. For Google’s advertising customers, the team I worked with (Brand Insights) was interested in measuring and classifying some metrics. For the first half of my internship, I researched on and documented possible different algorithms for which these metrics could be computed, and ended up choosing and implementing what I considered the best one. Then, using Google’s MapReduce system, I was able to compute and classify metrics for billions of existing data points. The team also had an internal UI prototype, to which I made a slight expansion by adding a time-range selection feature for which metrics could be computed. The 2016 Software Engineering Internship in Boston was decidedly more involved, and was a Machine Learning project. I had to preprocess data from multiple internal sources to extract features for thousands of entities, train the data on a classifier using classic machine learning algorithms (Adaptive Boosting, Winnow, Random Forest), and sort of play around with the parameters until the accuracy was satisfactory. Then I had to integrate the trained classifier into the pipeline that fetched these entities, so that it could generate and classify new unlabeled data. I also got to take a 20-hour ML course to complement my coding work, making for a very engaging summer. Beyond reading and writing code, I also had to give presentations, create documentations, attend team meetings, and quite memorably attend the company’s weekly TGIF meeting, which actually takes place on Thursdays. It occurs live in the Mountain View headquarters, and streams to other Google offices worldwide. Larry Page and Sergey Brin, the Google co-founders, often lead the meetings, and talk about the state of the company. Different teams also talk about their products and give demos. At my first TGIF meeting, with my bright Noogler hat on, I grabbed some wings, sat somewhere in the back, facing huge screens streaming from Google HQ and a ripple of chatter. I remember thinking, This is really happening. ** And being a Googler didn’t end when I wrote my last bit of code for the day. Whether it was with my team, or with other Googlers drawn from different teams in the office, we were often united in non-technical endeavors. About a month into my LA internship, I joined several Googlers at Venice Beach for a few hours. Dozens of footprints in the sand tracked our path as we picked up as much trash as we could and disposed of them. The people in my immediate vicinity on that afternoon constantly shifted, whether it was Emilia, my Engineering Practicum Host, or other interns or engineers I hadn’t met before that day. Conversation shifted with them, but it felt light and easy, comfortable. I also ended up spending a few hours one week just patrolling the Los Angeles Office. My eager self had signed up to be part of a group of Googlers giving high school kids a tour of the building, and at that point, I was still getting lost. So I learned where the cafes were, and the numerous microkitchens, and the Game Room, and the huge Google Earth device that let you see any location in the world on multiple large screens surrounding you. The tour went great, although at one point I was certain I would emerge with some of the kids into some strange new room and suddenly have no idea where we were, forcing us to spend an eternity in that subsection of the office. On the bright side, no matter where we were, we wouldnt have to walk for long to find a microkitchen stuffed with snacks. One of my favorite memories from that internship was probably the nugget eating contest my Brand Insights team had. The goal was to eat fifty McNuggets in sixty minutes. The reward, aside from all that free food, was immortalizationyour picture would go up on the team’s Hall of Fame wall. We sat outside, surrounded by boxes of Nuggets and napkins and drinks. The timer was set, and we went in immediately. Fifty nuggets in an hour seemed like nothing to me, a confidence that didn’t waver until about 15 nuggets in. Then, my pace slowed, but I kept on, relentless. About forty-seven nuggets in, I gave up. Yes, I only needed three more nuggets, but I was pretty sure I’d explode at that point if another molecule of food found its way into my mouth. Emilia, my project host, absolutely destroyed all fifty of her nuggets, in a display of effortlessness that still amazes me to this day. That summer, I would also attend the Special Olympics with Googlers at the University of Southern California. I would spend some Saturdays walking dogs with fellow engineers (I got attached to a very energetic Beagle). I would take part in a karaoke contest with interns in which my inner Taylor Swift came roaring out, unleashed. And I would share some of my writing with Googlers. Those unexpected e-mails of “Hey I read this and thought it was wonderful” always made my week. My internship at Google was about good code and putting what I’d learned at MIT to great use. It was about newfound confidence, bolstered by a chance they took on me and the support my project hosts gave me. It was about rediscovering Computer Science, and realizing that when you put together a band of the brightest minds in the world, what you create more closely resembles sorcery than machinery. It was about people who loved their work, and were more than their work. It was about excellent food, and new friends, and going to bed each night feeling incredibly content. One of the things that especially stood out to me was the mostly clean separation between “work” and “life”. At MIT, even when you weren’t doing problem sets, the specter of undone work, unmet deadlines hung around you at every moment. 3 P.M. was just as potential a time to be doing some work at 3 A.M. But for both summers, while I did occasionally have to work overtime, as soon as I logged out and left, there was no lingering specter. It made for a great balance that sometimes gets missing at MIT. There were off-kilter moments at times, whether it was from noticing how few engineers of color were around (although Google’s efforts at diversity are immense and well-documented), or just from my own anxiety kicking in right before a presentation. However, the memories of that summer are imprinted in a hallway of all my best life memories. And just before my last internship ended, when I received the e-mail about interest in moving forward, I already knew what I wanted to do. ** In September 2016, I accepted a full-time Software Engineering job offer from Google. I’ll be starting sometime in September of this year, in their New York Office. Needless to say, I am beyond excited. In just a few days, I graduate from MIT, a crazy fact I still haven’t quite processed yet. But as the chapter on the Institute reaches a conclusion that part of me isn’t entirely ready for, a whole new book awaits. And I can’t wait to turn the page. Post Tagged #Career Fair

Saturday, May 23, 2020

Mrs. Ferguson s An Emotional Breakdown - 1646 Words

Mrs. Ferguson sniffled. Out of her nose oozed a slimy strand of pale, green liquid. Her runny nose was not caused by the cold, though it was very cool this time of year. No, she had in fact just lost her 45 year old husband, who had been murdered. When she had received word of the tragic event, she had suffered an emotional breakdown. She had desperately demanded to know who the killer was, but the man who she was speaking with on the phone had told her that the police had no idea, but they were investigating. She had hung up, and cried constantly. By the time her tears had stopped spilling, her cheeks had been covered with a crusty coating of dried tears.Need descriptive words. Currently, she was at the local cemetery, where all around, freshly fallen snow twinkled and glistened on the once green ground. The pale gray pathway had been shoveled, however, so that people could get around the cemetery easily. Mrs. Ferguson was listening attentively to the pastor, who was describing Mr. Ferguson’s life. Only Mr. Ferguson’s close family had been invited to attend the funeral, so they all knew every detail of his life, but it was common practice to read it all anyways. Bobby Ferguson had been a doctor. An anesthesiologist, to be precise. Whenever someone was to have surgery or give birth, for example, he would give them medicine to make them sleep until the pain of it was over. Now, Mrs. Ferguson thought gloomily, it was his turn to rest. It had been Bobby’s goal to be aShow MoreRelatedReflective Account of ....10187 Words   |  41 Pagesprocedures at ED such as Intubation of patient, Cardio Pulmonary Resuscitation (CPR), Continues Bladder Drainage (CBD), Chest Tube Insertion, Incision and Drainage (ID), Toilet and Sutures (TS) etc. I acknowledge that my practice may not always be evidence based and lack of understanding of the wound infection from TS procedure. I do fully realize that as a health care professional, I have a duty of care for every patient (Nursing Midwifery Council, 2004). Reflection has become an important componentRead MoreAn Assessment Of Competencies Of Team Leaders9717 Words   |  39 Pagesc. That any specific direction or advice received as to the conduct of the work is properly acknowledged. d. I understand that the Report becomes the property of the College upon submission. †¢ Student Last Name:†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.Jarvis †¢ Student First Name(s):†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦..Jerrod †¢ Student Identification Number:†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.1009010056 †¢ Programme/Department of:†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦....Occupational Safety Health and the Environment. †¢ Course Number and Course Title:†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦..OSH 260 Research Paper †¢ Thesis/Report Title:†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ An AssessmentRead MoreStephen P. Robbins Timothy A. 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Using precision-engineered components and a suspended sub-chassisRead MoreStrategic Marketing Management337596 Words   |  1351 Pagespreparing fo r the Marketing Planning paper in the CIM’s Diploma examinations âž ¡ Marketing practitioners who will benefit from a comprehensive review of current thinking in the field of strategic marketing planning, implementation and control. Richard M S Wilson Colin Gilligan Overview of the book’s structure 1 Introduction Stage One Where are we now? Strategic and marketing analysis 2 Marketing auditing and the analysis of capability 3 Segmental, productivity and ratio analysis 4 MarketRead MoreCase Study148348 Words   |  594 Pagesfor driving are relevant. PESTELs can often seem somewhat inconclusive, so it is important to pull out key issues and conclusions. The increasing hostility to drinking (under P and L) and the rise of Asian economies and southern Europe (under E S) seem particularly important trends. One way of drawing some simple conclusions is to assess the overall balance (positive or negative) under each of the PESTEL headings: in the case of the European brewing industry, most of the headings are likely toRead MoreMarketing Mistakes and Successes175322 Words   |  702 PagesUniversity of Minnesota and George Washington University. His MBA and Ph.D. are from the University of Minnesota, with a BBA from Drake University. Before coming into academia, he spent thirteen years in retailing with the predecessor of Kmart (S. S. Kresge), JCPenney, and Dayton-Hudson and its Target subsidiary. He held positions in store management, central buying, and merchandise management. His first textbook, Marketing: Management and Social Change, was published in 1972. It was aheadRead MoreEssay on Fall of Asclepius95354 Words   |  382 Pagesthe first thing he touched: a large knife. With a look of desperation apparent on his face, Thomas held the knife outwards. Stay back! he screeched. Stay back, or I-Ill stab you! The stranger took no notice to Thomas threat or unstable emotional state. The stranger moved forward and let the knife slide into him. Thomas was horrified at what this person was doing. He was killing himself! Thomas finally gathered enough of his mentality back to really notice what was wrong with this personRead MoreManaging Information Technology (7th Edition)239873 Words   |  960 Pagesand permission should be obtained from the publisher prior to any prohibited reproduction, storage in a retrieval system, or transmission in any form or by any means, electronic, mechanical, photocopying, recording, or likewise. To obtain permission(s) to use material from this work, please submit a written request to Pearson Education, Inc., Permissions Department, One Lake Street, Upper Saddle River, New Jersey 07458. Many of the designations by manufacturers and sellers to distinguish their

Tuesday, May 12, 2020

Frederick Douglass Journey From Slavery To Freedom Essay

Having been born into slavery, Frederick Douglass like all slaves has no freedom, possessions, and little to no education or family members. Worst of all, he must succumb to the physical and mental brutality associated with being a slave, in order to survive on the plantations on which he lives. Douglass defies the expectations bestowed upon him by slavery and does not choose the path of a normal and subservient slave by actively trying to escape. After escaping slavery, Douglass decides to compose a narrative of his life and experiences as a slave titled, The Narrative Life of Frederick Douglass, in which he illustrates his journey from slavery to freedom. This narrative serves as a roadmap to freedom, in that the travel along the road is†¦show more content†¦He and the other slaves are also worked tirelessly from sunrise to sundown and often abused on Colonel Lloyds plantation, mostly at the hands of the overseers, Mr. Severe, Mr. Hopkins (who replaces Mr. Severe when he d ies), and Mr. Gore (who replaces Mr. Hopkins when he is fired for not being aggressive enough) As mentioned in the letter from Wendell Phillips, Douglass is a slave in Maryland, which at the time, is one of the areas in the United States in which slavery is less brutal. One could only imagine how differently Douglass’ narrative would be if he had been a slave anywhere else. The next stop on Douglass’ journey is leaving the Colonels plantation and beginning his education in Baltimore. Getting the news that he was leaving was the best thing that happened to Douglass while he was at Colonel Lloyds plantation. As his departure neared, Douglass began to clean himself and became excited at the fact that we would get to wear pants in Baltimore. Looking back, Douglass says that leaving the plantation is a turning point itself because if he had not, he might have never escaped. Being moved showed Douglass more of the world and provided opportunities. As soon as he arrives in Baltimore, Douglass does not know what to think of his new mistress, Mrs. Auld, and is confused by herShow MoreRelatedFrederick Douglass How I Learned to Read and Write939 Words   |  4 PagesFrederick Douglass How I Learned to Read and Write During the 1800’s, the institution of slavery was still ongoing in the few slave states left in America. Slavery was still proving to be unjust and unfair, not allowing for African Americans to be considered equals. However, some slaves were able to overcome the many restrictions and boundaries that slavery forced upon them. In Frederick Douglass’ essay â€Å"Learning to Read and Write,† Douglass portrays himself as an intelligent and dignifiedRead MoreCompare and Contrast the Representation of the Figure of the Slave, and of the Theme of Freedom, in Douglass’s â€Å"Narrative† and Twain’s â€Å"Adventures of Huckleberry Finn†.1445 Words   |  6 Pagesrepresentation of the figure of the slave, and of the theme of freedom, in Douglass’s â€Å"Narrative† and Twain’s â€Å"Adventures of Huckleberry Finn†. The two novels that I am studying are â€Å"The Adventures of Huckleberry Finn† by Mark Twain, and â€Å"The Narrative of Frederick Douglass – Written by Himself†. Both these texts give us an insight into the life of slavery and the societal beliefs of the South in America in the nineteenth century. The theme of freedom and the figure of the slave are two common aspects ofRead MoreSlaves Narratives: Frederick Douglass, Olaudah Equiano Essay1477 Words   |  6 PagesSojourner Truth, Frederick Douglass, and Olaudah Equiano all have extremely interesting slave narratives. During their lives, they faced plenty of racist discrimination and troubling moments. They were all forced into slavery at an awfully young age and they all had to fight for their freedom. In 1797, Truth was born into slavery in New York with the name of Isabella Van Wagener. She was a slave for most of her life and eventually got emancipated. Truth was an immense women’s suffrage activis t. SheRead MoreAn Analysis Of Learning To Read And Write By Frederick Douglass872 Words   |  4 PagesFrederick Douglass was once a slave with an opportunity that no other slaves have obtained. Douglass have spent the rest of his life educating himself, either by self-taught or someone else helping him to learn. At the time period, it was forbidden for the slaves to educate or to be educated. Douglass was lucky enough to even receive this chance to educate himself. Despite his determination to educate himself, he is still human. There are obstacles in his journey that prevented him from moving onRead More Martin Luther King Jr. and Frederick Douglass Essay1390 Words   |  6 PagesMartin Luther King Jr. and Frederick Douglass When comparing two essays, there are many different aspects that the reader can look at to make judgments and opinions. In the two essays that I choose, MARTIN LUTHER KING JR. Letter from Birmingham Jail, and FREDERICK DOUGLASS From Narrative of the Life of Frederick Douglass, an American Slave, there were many similarities, but also many differences. Some of them being, the context, style, structure and tone. Many times when readingsRead MoreFrederick Douglass And Malcolm X Essay1237 Words   |  5 Pagestwo works from African American literature reveals that there is no greater accomplishment than learning to read and write. Literacy is what allows us to gain knowledge through learning. This topic is important because based on a study conducted by the U.S Department of Education and the National Institution of Literacy, 32 million adults in the U.S are still unable to read and write and African Americans are expected to make up nearly half of that amount. In both F redrick Douglass’ â€Å"LearningRead MoreNarrative of the Life of Frederick Douglass: Logically Emotional Appeal942 Words   |  4 PagesNarrative of the Life of Frederick Douglass: Logically Emotional Appeal Narrative of the Life of Frederick Douglass, is a moving written account of Frederick Douglass’ harrowing experiences as a slave, and his journey into freedom. In his critical essay â€Å"Douglass and Sentimental Rhetoric,† Jefferey Steele argues, that despite being objective, Douglass’ account is mixed with Pathos, complicating the straightforward chronicle. While pathos is evident in the text, it does not complicate the memoir’sRead MoreThe Library Card By Richard Wright1367 Words   |  6 Pagestwo essays, â€Å"Learning to Read and Write† by Frederick Douglass and â€Å"The Library Card† by Richard Wright, the two authors face many obstacles in their lives. Frederick Douglass is a slave who has a desire to gain knowledge regardless of the obstacles. Richard Wright is an African American man who lives in the South during the Jim Crow Laws and also has a yearning to attain more information about the life he lives. A previous EOF student, Corey James’ reaction to the essays written by Frederick DouglassRead MoreThe Narrative of the Life of Frederick Douglass: the Formation of Iden2208 Words   |  9 PagesThe Narrative of the Life of Frederick Douglass: An Analysis of the Formation of Identity You have seen how a man was made a slave; you will now see how a slave was made a man. Ââ€"Frederick Douglass The Narrative of the Life of Frederick Douglass, An American Slave details the progression of a slave to a man, and thus, the formation of his identity. The narrative functions as a persuasive essay, written in the hopes that it would successfully lead to hastening the glad day of deliveranceRead MoreTrickery in Narrative of the Life of Frederick Douglass by Frederick Douglass1880 Words   |  8 Pagesthus they do not survive. In Narrative of the Life of Frederick Douglass by Frederick Douglass, Douglass harnesses the ability to conform to the world of trickery and conveys his journey to freedom. Through his appeal to pathos, use of dramatic asides, and application of anecdotes, Douglass expresses the necessity of slaves to play the game of trickery to survive in the world of tricksters. Effectively establishing an appeal to pathos, Douglass emphasize his raw emotions to the reader, allowing the

Wednesday, May 6, 2020

Teamlease Putting India to Work Legally Free Essays

Roxanne Koprowski March 18, 2013 IB605 Teamlease: Putting India to Work Legally 1. ) Growth is extremely important for TeamLease’s future, especially since their business model was to â€Å"grow so fast that no one can shut you down. † They also wanted to create a people supply chain as well as becoming India’s largest employer. We will write a custom essay sample on Teamlease: Putting India to Work Legally or any similar topic only for you Order Now With those goals in mind, their ultimate achievement is to grow substantially. In order to remain India’s largest employer, they had to keep up with the explosive growth and competition in the telecommunications, financial services, and retail sectors. 2. ) Going forward, TeamLease has faced a few challenges along the road. First, TeamLease decided to move from a decentralized to a centralized structure for operations, causing fear and resistance from clients who were afraid of the loss of personalized services and fear from TeamLease employees who disliked the idea of relocating. TeamLease also had a difficult time filling open positions. Many people were registered with the government-run employment exchanges and many of these people were not fully qualified for the job. TeamLease also tried to partner with training companies but there was no training company that would accept their concept of paying for their services only after their trainee has been placed with a job. They also took a big hit during the 2009 recession causing the open job market to drop dramatically and as well as a decrease in client support. . ) The competitors that worry me the most are Addeco and Randstad. Addeco seems to be the largest HR staffing service company followed by Randstad. Addeco is a major threat with over 33,000 employees and 5,500 branches, in over 60 countries. Randstad has 28,700 employees, 3,500 branches, in over 40 countries. TeamLease on the other hand has 75,000 employees in 600 branches. TeamLease may have more employees, but Randstad and Adecco seems to have mo re qualified employees and are more spread out worldwide. TeamLeast has the least amount of branches among its top competitors. 4. ) I believe that TeamLease should put more money into staffing and training in order to have more suitable and a more experienced staff in order to maintain competitive advantage. They should also try to increase or spread out more of their branches to other countries. TeamLease should also put more effort into marketing and their advertising campaign. Last, they should consider offering employee incentives such as days off or bonuses’. How to cite Teamlease: Putting India to Work Legally, Papers

Friday, May 1, 2020

Edith Whartons Fantasy Is An Escape From Winter Essay Example For Students

Edith Whartons Fantasy Is An Escape From Winter Essay Edith Whartons Fantasy is an Escape from WinterFantasy is an Escape from Winter Ethan Frome, the title character of Edith Whartons tragic novel, lives in his own world of silence, where he replaces his scarcity of words with images and fantasies. There is striking symbolism in the imagery, predominantly that of winter which connotes frigidity, detachment, bleakness and seclusion. Twenty-eight year old Ethan feels trapped in his hometown of Starkfield, Massachusetts. He marries thirty-four year old Zeena after the death of his mother, in an unsuccessful attempt to escape the silence, isolation, and loneliness of life (Lawson 71).Several years after their marriage, cousin Mattie Silver is asked to relieve Zeena, a gaunt and sallow hypochondriac, of her household duties. Ethan finds himself falling in love with Mattie, drawn to her youthful energy, as, The pure air, and the long summer hours in the open, gave life and elasticity to Mattie (Wharton 60).Ethan is attracted to Mattie because she is the antithesis of Zeena. While Mattie is young, happy, healthy, and beautiful like the summer, Zeena is seven years older than Ethan, bitter, ugly and sickly cold like the winter (Lewis 310). Zeenas strong, dominating personality emasculates Ethan, while Matties feminine, effervescent youth makes Ethan feel like a real man. Contrary to his characteristic passiveness, he defies Zeena in Matties defence, You cant go, Matt! I wont let you! Shes always had her way, but I mean to have mine now - (Wharton 123).To Ethan, Mattie is radiant and energetic. He sees possibilities in her beyond his trite life in Starkfield, something truly worth standing up for. Her energy and warmth excite him and allow him to escape from his lonely, monotonous life. While Zeena is visiting an out of town doctor, Ethan and Mattie, alone in the house, intensely feel her eerie presence. The warmth of their evening together is brought to an abrupt end by the accidental breaking of Zeenas prized dish. Zeenas fury at the breaking of an impractical pickle dish exemplifies the rage she must feel about her useless life. That the pickle dish has never been used makes it a strong symbol of Zeena herself, who prefers not to take part in life (Lawson 68-69). Ethans response to Zeenas rage was silence. Just as Ethan lives in silence, so too does his wife. The total lack of communication between the silent couple is a significant factor in Ethans miserable marriage. Ethan kept silent in his dealings with his wife, to check a tendency toimpatient retort he had first formed the habit of not answeringher, and finally thinking of other things while she talked(Wharton 72).Zeena is the cold and ugly reality from which Ethan tries to escape in his dreams of a life with Mattie. He is happy only when imagining his life with Mattie. The night that they are alone, he pretends that they are married. Often when they are together, he fantasizes that Zeena is dead and that he and Mattie live together in blissful devotion. Ethan deludes himself because, as a prisoner of circumstance, his only escape is illusion. His happiness in the company of Mattie is the product of a self-deception necessitated by his unhappy marriage to Zeena, the obstacle to a life long relationship with Mattie. After the night of the broken dish, Ethan and Mattie finally articulate their feelings for each other, and are forced to face the painful reality that their fantasies can not come true:The return to reality was as painful as the return to consciousness after taking an anaesthetic. His body and brain ached with indescribable weariness, and he could not think of nothing to say or do that should arrest the mad flight of the moments (Wharton 95). Zeena herself, from an oppressive reality, had faded into an insubstantial shade (Wharton 39). Her hypochondria is her outlet, just as Ethans world of fantasy is his. .ua47a892a8c08ff8a4971f65ecdbbd150 , .ua47a892a8c08ff8a4971f65ecdbbd150 .postImageUrl , .ua47a892a8c08ff8a4971f65ecdbbd150 .centered-text-area { min-height: 80px; position: relative; } .ua47a892a8c08ff8a4971f65ecdbbd150 , .ua47a892a8c08ff8a4971f65ecdbbd150:hover , .ua47a892a8c08ff8a4971f65ecdbbd150:visited , .ua47a892a8c08ff8a4971f65ecdbbd150:active { border:0!important; } .ua47a892a8c08ff8a4971f65ecdbbd150 .clearfix:after { content: ""; display: table; clear: both; } .ua47a892a8c08ff8a4971f65ecdbbd150 { display: block; transition: background-color 250ms; webkit-transition: background-color 250ms; width: 100%; opacity: 1; transition: opacity 250ms; webkit-transition: opacity 250ms; background-color: #95A5A6; } .ua47a892a8c08ff8a4971f65ecdbbd150:active , .ua47a892a8c08ff8a4971f65ecdbbd150:hover { opacity: 1; transition: opacity 250ms; webkit-transition: opacity 250ms; background-color: #2C3E50; } .ua47a892a8c08ff8a4971f65ecdbbd150 .centered-text-area { width: 100%; position: relative ; } .ua47a892a8c08ff8a4971f65ecdbbd150 .ctaText { border-bottom: 0 solid #fff; color: #2980B9; font-size: 16px; font-weight: bold; margin: 0; padding: 0; text-decoration: underline; } .ua47a892a8c08ff8a4971f65ecdbbd150 .postTitle { color: #FFFFFF; font-size: 16px; font-weight: 600; margin: 0; padding: 0; width: 100%; } .ua47a892a8c08ff8a4971f65ecdbbd150 .ctaButton { background-color: #7F8C8D!important; color: #2980B9; border: none; border-radius: 3px; box-shadow: none; font-size: 14px; font-weight: bold; line-height: 26px; moz-border-radius: 3px; text-align: center; text-decoration: none; text-shadow: none; width: 80px; min-height: 80px; background: url(https://artscolumbia.org/wp-content/plugins/intelly-related-posts/assets/images/simple-arrow.png)no-repeat; position: absolute; right: 0; top: 0; } .ua47a892a8c08ff8a4971f65ecdbbd150:hover .ctaButton { background-color: #34495E!important; } .ua47a892a8c08ff8a4971f65ecdbbd150 .centered-text { display: table; height: 80px; padding-left : 18px; top: 0; } .ua47a892a8c08ff8a4971f65ecdbbd150 .ua47a892a8c08ff8a4971f65ecdbbd150-content { display: table-cell; margin: 0; padding: 0; padding-right: 108px; position: relative; vertical-align: middle; width: 100%; } .ua47a892a8c08ff8a4971f65ecdbbd150:after { content: ""; display: block; clear: both; } READ: Business 2 Essay It is adventurous in contrast to her monotonous marriage (McDowell 66). Sickly Zeena is able to manipulate her husband using her frail health to justify her bitter personality. When she spoke it was only to complain (Wharton 72).Ethan and Mattie attempt to preserve their happiness and remain together the only way they can, in death. At this point, Mattie inadvertently becomes the cause of Ethans tragic suffering.The aborted suicide attempt leads to their tragic fate, living a life of physical suffering, so badly injured that former invalid, Zeena is forced to care for them.If shed ha died, Ethan might ha lived (Wharton 181). It is horribly ironic that, as a result of the accident, Mattie, the source of Ethans earlier joy, is now an additional trial in an already depleted life. Where Ethan was once uplifted by virtue of Matties being, he is now burdened by her very presence. Tragically, time only accentuated his suffering instead of alleviating it. After suffering so long with the sickly Zeena, Ethan now has to exist with the horribly deformed remains of a once beautiful, sensitive, and loving girl. Once again surrendering himself to the forces of isolation, silence, darkness, cold, and death-in-life (McDowell 68). The setting for Ethan Frome is winter. Edith Wharton, the author, chose winter as a theme because it symbolizes the emotional and physical isolation, cold, darkness, and death that surround Ethan. Similarly, the name of the town Starkfield is symbolic of Ethans arid life. Stark denotes the harsh winters causing barren, lifeless landscape, with lifeless and devastated people (Howe 113). The narrator notes this connection; During the early part of my stay I had been struck by the climate and the deadness of the community (Wharton 8). Wharton emphasizes the rigor of life in a harsh land with its rocky soul, its cold winters, and its bleak, desolate beauty (McDowell 65). Wharton writes: The snow had ceased, and a flash of watery sunlight exposed the house on the slope above us in all its plaintive ugliness.The black wraith of a deciduous creeper flapped from the porch, and the thin wooden walls, under their worn coats of paint, seemed to shiver in the wind that had risen with the ceasing of the snow (20). The downtrodden image painted in this quotation describes the environment, as well as describing Ethan. Just as his house was once new and beautiful but is now torn by many harsh winters in Starkfield, so to was Ethan. The ravages of winter destroy both mans will to survive and the buildings he constructed to shield him from this environment. As the narrator explains, I had a sense that his loneliness was not merely the result of his personal plight, tragic as I guessed that to be, but had in it the profound accumulated cold of many winters (Wharton 15). The description of the weather is also used to foreshadow events and set the mood. Once Ethan and Mattie decide to take their lives, as if to suggest that something will go wrong, the sky is described as, swollen with clouds that announce a thaw, hung as low as before a summer storm (Wharton 167). This is just one of many times in the novel when the climate is used to indicate foreboding events. The weather imagery is used in character development and depiction. After the accident, He seemed a part of the mute melancholy landscape, an incarnation of its frozen woe, with all that was warm and sentient in him fast bound below the surface (Wharton 14). When Mattie first arrives in Starkfield, her presence is perceived as, a bit of hopeful young life, like the lighting of a fire on a cold hearth (33). In contrast to Matties radiant warmth, Zeena is described as wintery and unappealing: She sat opposite the window, and the pale light reflected from the banks of snow made her face look more thanusually drawn and bloodless, sharpened the three parallel creases betwe

Saturday, March 21, 2020

Scenario Analysis In Finance Essay Example

Scenario Analysis In Finance Essay Finance Scenario Analysis Introduction Scenario 1: Increased expenses used in financing Increasing the level of expenses alongside increased revenues in the overall leads to a decrease in the EBIT. The increase in the amount of expenses happens to be at a higher rate than that the increase in the revenue and this depreciates the level of operating income obtained after deducting expenses. Expenses such as advertising, sales and distribution as well as administration expenses have a heavy weight on the income level and this leads to the reduction in the profits level of the company. From the analysis, it is clear that the increase in the amount of corporate expenses as well as the selling, general and administrative expenses from (2.2M, 12.9M) in 1997 to (4.2M, 30.7M) in 1999 significantly affects the operating income. Ideally, selling, general and administrative expenses take a significant portion of the expenses. Irrespective of the tax amount charged, the net profit after taxes will always decrease with increase in the variable and fixed expenses. In the above scenari o, EBIT decreased from $157,501 in 2001 to $252,034 in year 2004. We will write a custom essay sample on Scenario Analysis In Finance specifically for you for only $16.38 $13.9/page Order now We will write a custom essay sample on Scenario Analysis In Finance specifically for you FOR ONLY $16.38 $13.9/page Hire Writer We will write a custom essay sample on Scenario Analysis In Finance specifically for you FOR ONLY $16.38 $13.9/page Hire Writer Scenario 2: Financing assets through significant capital expenditure Ideally, increasing the amount of capital allocated to making capital expenditures through investment in assets is profitable and though leads to incurring of huge initial outlay, it results to increase in revenues especially when the items acquired are used in the generation of additional cashflows. The assets purchased have different payback times and while others take a short time to generate revenues which cover the costs incurred in purchasing them, others have long payback times but the overall aim was to generate an incremental cashflow which in this case can be seen to have increased from $2.035M in 1997 to 18.6M in 2001 and finally to $138.7 M in 2004. Scenario 3: Increasing debt ratio and earning per share The increase in debt ratio which is brought about by increasing borrowings from external sources can be seen to have a negative effect on the cashflows mainly because it leads to the reduction in the equity level. Failure of the organization to generate enough cashflows from utilizing its assets efficiently and to be in a position to repay off its debts is what makes the cashflows adverse. One of the consequence of this is reduced earnings per share since more money is used to pay off debts and less is distributed to the shareholders.

Thursday, March 5, 2020

Free Essays on Feminist Analysis Of Heartbreakers

This film is possibly a representation of both love and violence in relation to gender. The mother-daughter team in this movie use â€Å"love† to swindle men out of their money. Sigourney Weaver and Jennifer Love-Hewitt play Angela and Paige, the con artists that use their good looks and a long list of cons to get meals, hotel rooms, marriages, and hefty divorce settlements when something â€Å"accidentally† goes wrong. Heartbreakers (David Mirkin, 2001) is an exploration of femininity, sexuality, and the usage and affects on the male population and the women that posses these traits. Angela marries at the beginning of the movie, for the thirteenth time, and creates a scam involving her daughter, only to divorce Dean, (Ray Liotta) seventeen hours after the marriage. They get away with a three-hundred thousand dollar settlement, but do not realize that it won’t be the last they see of Dean. They end up in Palm Beach to try to con an old, heavy smoker, Tinsey (Gene Hackman). This is where Paige meets Jack, a man she initially wants to con out of his business; but since she is young, she falls in love with him instead. These women feel that men will only hurt them and leave them, so it is better to beat them at their own game, and then go ahead and take all of their assets. Angela, Paige’s mother, is inherently afraid of being alone, and eventually ends up conning her own daughter in order for her to stay with her. She is trying to protect her from love as well, because â€Å"love is pain†. She taunts and gets angry when she realizes that Paige has fallen in love, reaffirming that Paige would be no good at conning on her own because of the fact that she will fall in love with the men. Woods, 2 At one point when Paige calls Jack (the one she falls in love with) cute, Angela reprimands her by saying â€Å"cute leads to feeling; feeling leads to screwing; and screwing leads to getting screwed.† Angela insists that they ... Free Essays on Feminist Analysis Of Heartbreakers Free Essays on Feminist Analysis Of Heartbreakers This film is possibly a representation of both love and violence in relation to gender. The mother-daughter team in this movie use â€Å"love† to swindle men out of their money. Sigourney Weaver and Jennifer Love-Hewitt play Angela and Paige, the con artists that use their good looks and a long list of cons to get meals, hotel rooms, marriages, and hefty divorce settlements when something â€Å"accidentally† goes wrong. Heartbreakers (David Mirkin, 2001) is an exploration of femininity, sexuality, and the usage and affects on the male population and the women that posses these traits. Angela marries at the beginning of the movie, for the thirteenth time, and creates a scam involving her daughter, only to divorce Dean, (Ray Liotta) seventeen hours after the marriage. They get away with a three-hundred thousand dollar settlement, but do not realize that it won’t be the last they see of Dean. They end up in Palm Beach to try to con an old, heavy smoker, Tinsey (Gene Hackman). This is where Paige meets Jack, a man she initially wants to con out of his business; but since she is young, she falls in love with him instead. These women feel that men will only hurt them and leave them, so it is better to beat them at their own game, and then go ahead and take all of their assets. Angela, Paige’s mother, is inherently afraid of being alone, and eventually ends up conning her own daughter in order for her to stay with her. She is trying to protect her from love as well, because â€Å"love is pain†. She taunts and gets angry when she realizes that Paige has fallen in love, reaffirming that Paige would be no good at conning on her own because of the fact that she will fall in love with the men. Woods, 2 At one point when Paige calls Jack (the one she falls in love with) cute, Angela reprimands her by saying â€Å"cute leads to feeling; feeling leads to screwing; and screwing leads to getting screwed.† Angela insists that they ...

Tuesday, February 18, 2020

Management case Study Research Paper Example | Topics and Well Written Essays - 1750 words

Management case Study - Research Paper Example This paper will highlight some of these strategies and the possible outcome in its recommendation (Griffin) Zynga is a social gaming provider headquartered in San Francisco, California. The company develops social games that operate on mobile phone platform such as Apple iOS and android. In 2009 the company reached 10 million daily active users within six weeks (Abbey, 2009).The management of zynga need to put in place certain measure in order to double its customers and revenue. This case study will highlight the achievement of the company, and future planning to help the company compete favourably with others and stay afloat (Abbey, 2009). The company has a record of hitting 10million active daily users in the first six months, this is a great achievement but to maintain this number and even double them the management of the company need to put in place certain measures. This paper highlights some of the considerations that need to be put in place in order to achieve more. The company strength will rely mainly on formation of synergies with other companies where the synergy is the urge to form partnership relationship with other companies of similar goal and interest. There is positive and negative consequence of synergies and group cohesion needs to be considered. As a group become more cohesive, communication between members increases. In addition satisfaction increases as the group provides friendship and support against outside threat (Hitt & Jamie, 2007). There are negative aspects of group cohesion that affect the decision made by individual parties hence affecting group effectiveness. Issues may arise such as risk shift phenomenon, where there is a tendency of a group to make risky decision that an individual party would have handled. There may also be polarization, individual in a group can have moderate stance on an issue, and having discussed in a

Monday, February 3, 2020

Racial Constructs Essay Example | Topics and Well Written Essays - 1000 words - 1

Racial Constructs - Essay Example y of individuals is the cultural issues and environment as in the article, race concepts in medicine, but all individuals if subjected to the same conditions and environment will think and act the same despite the race. On the contrary, it is true to some extent that according to Jethro’s message with are right as per the movie district nine. Forcibly, Van der Merwe struggles to relocate the aliens who had come in a ship and was settling in a section of South Africa. Since humans could not operate the weapons that the aliens had, the growth of a claw in the place of a hand by van, propelled him to be a central operator of both the Nigerian gangsters and Security Company. The Nigerian gangs were exploiting the aliens by selling them cat foods. However, the above to some extent portrays the evidence of the fact that whites are always right. This is so because everyone was afraid to relocate the aliens and the only torch bearer was a fan, whom manages to maneuver through to become a hero in deals and designs of relocating the aliens who were rejected by the residents. With his racial complexion of white, Van der Merwe seams to be successful, and at this point is when there is approving of the t erm whites are right. Here, the hero tactically finds an idea that the only way to operate the alien’s weapons is by growing a lobster claw in the place of his hand. With the above claws, he manages to be a security company and at the same time, he operates the Nigerian gangster ideas by exploiting the aliens from the cat food being sold to them. All the above was for the efforts of relocating the aliens, though it was not an easy task to relocate them. Having put that across, the fact remains that Van der Merwe used his brains to explore the aliens by not only growing the claws but also incorporating those aliens who proved to be intelligent and those that had human emotions. It is evident according to the movie district nine that the aliens in the movie are of the

Sunday, January 26, 2020

MGMT Methylation Status and Glioblastoma Multiforme Outcome

MGMT Methylation Status and Glioblastoma Multiforme Outcome ABSTRACT Background: O6 – methylguanine-methyltransferase (MGMT) promoter methylation has been associated with increased survival among patients with glioblastoma multiforme (GBM) who were treated with various alkylating agents. We examined the relationship between MGMT methylation status and clinical outcome in newly diagnosed GBM patients treated with BCNU wafers (Gliadel ®). Methods: MGMT promoter methylation in DNA from 122 newly diagnosed GBM patients treated with Gliadel was determined by a Quantitative methylation-specific polymerase chain reaction assay (QMSP) and correlated with overall survival (OS) and recurrence-free survival (RFS). Results: The MGMT promoter was methylated in 40 (32.7%) of 122 patients. Overall median survival was 13.5 months (95%CI: 11.0-14.5) and recurrence-free survival (RFS) was 9.4 months (95%CI: 7.8-10.2). After adjusting for age, KPS, extent of resection, temozolomide (TMZ) and radiation therapy (RT), newly diagnosed GBM patients with MGMT methylation who were treated with Gliadel had a 15% reduction in hazard of death compared to patients with unmethylated MGMT (Hazard ratio: 0.85, 95%CI: 0.56-1.31). Patients aged over 70 with MGMT methylation and treated with Gliadel had a significantly longer median survival of 13.5 months compared to 7.6 months in patients with unmethylated MGMT (p=0.027). A similar significant difference was also found in older patients with a median recurrence-free survival of 13.1 versus 7.6 months (p=0.01) for MGMT methylated and unmethylated, respectively. Conclusions: Methylation of the MGMT promoter in newly diagnosed GBM patients who were treated with Gliadel followed by RT and TMZ, was associated with significantly improved survival compared to the non-methylated patient population with similar treatment. For the elderly population, methylation of the MGMT promoter was associated with significantly better OS and RFS. INTRODUCTION Glioblastome multiforme (GBM) is the most common primary brain tumor, with a median survival of less than two years [1]. To date, only two different alkylating agents have been shown to be consistently associated with prolonged survival – temozolomide (TMZ) and the locally delivered BCNU wafers (Gliadel) [1-3]. Gliadel wafers (Eisai Inc. for Arbor Pharmaceuticals, LLC) are implanted and locally deliver Carmustine (also known as (1,3-bis(2-chloroethyl)-1- nitrosourea (BCNU)) at the site of tumor resection, allowing for a higher concentration of local chemotherapeutic doses while minimizing systemic adverse effects [2-4]. These wafers provide a controlled- release form of local chemotherapy for approximately 3 weeks [4, 5]. Methylation of the MGMT promoter in gliomas was found to be an important predictor of the tumor responsiveness after several cytotoxic regimens [6], including BCNU treatment [7]. It was found that expression of the DNA repair protein, O6 – methylguanine-methyltransferase (MGMT), results in GBM resistance to alkylating agents. Alkylating agents cause cell death by binding to DNA, most commonly to the O6 position of guanine, and forms cross-links between adjacent DNA strands. This cross-linking of double strand DNA is inhibited by the cellular DNA-repair protein MGMT. In this study, through a unique analysis of 122 patients with newly diagnosed GBM who were treated with Gliadel, we retrospectively examined the association between MGMT promoter methylation status and survival. METHODS Patients and Tumor Specimens We retrospectively reviewed 185 patients with newly diagnosed GBM who received Gliadel after tumor resection, at Johns Hopkins Hospital in Baltimore, USA, between July 1997 and December 2006. Of these patients, only 122 patients had stored samples that were available for MGMT analysis. The clinical, radiological and hospital course of these patients were retrospectively reviewed. Age and gender were recorded, as well as Karnofsky performance score (KPS) at time of diagnosis, tumor location, time to recurrence and dates of death were recorded. Overall survival (OS) was calculated from the time of surgery to death, and recurrence free survival (RFS) was calculated from the time of surgery to time of recurrence or censored at the last time of follow-up. GBM was histologically confirmed in all cases. Extent of surgical resection was determined based on a postoperative MRI performed Treatment Algorithm Gliadel wafers were typically not implanted in patients after tumor resection when the tumor largely extended into the ventricles or was multifocal. DNA Extraction After initial patient de-identification, all original histologic slides from the GBM specimens were reviewed to reconfirm the diagnosis of GBM by a senior neuropathologist (PB). A representative block with tumor was retrieved for DNA extraction. Histologic slides from the formalin-fixed, paraffin-embedded tissue were obtained. One representative slide was stained with HE and the tumor was marked by the senior neuropathologist (PB). An additional five correlating unstained 10 micron slides were also obtained. The tumor cells in the unstained slides were microdissected according to the marked HE stained reference slide. DNA was extracted from paraffin embedded tissue after xylene deparaffinization. The microdissected tissue was digested with 1% sodium dodecyl sulfate (SDS) and 200ug/mL proteinase K (Roche, Nutley, NJ) at 48 °C for 48 hours, followed by phenol/chloroform extraction and ethanol precipitation of DNA. Extracted DNA was dissolved in either LoTE (2.5 mM EDTA, 10 mM Trisâ⠂¬â€œHCl [pH 8]) or distilled water. Bisulfite Treatment Extracted DNA was subjected to bisulfite treatment, to convert unmethylated cytosine residues to uracil residues. Briefly, 2  µg genomic DNA from each sample was treated with bisulfite using the EpiTect Bisulfite kit (Qiagen, Valencia, CA) according to the manufacturer’s instructions. Converted DNA was stored at -80oC. Methylation Analysis Bisulfite-modified DNA was used as a template for fluorescence-based real-time PCR. Amplification reactions were carried out in triplicate in a final volume of 20  µL that contained 3  µL bisulfite-modified DNA; 600 nmol/L concentrations of forward and reverse primers; 200 nmol/L probe; 0.6 units platinum Taq polymerase (Invitrogen); 200  µmol/L concentrations each of dATP, dCTP, dGTP, and dTTP; and 6.7 mmol/L MgCl2. Primers and probes were designed to specifically amplify the promoter of MGMT and the promoter of a reference gene, ACTIN B; primer and probe sequences and annealing temperatures are provided in Table 1. Amplifications were carried out using the following profile: 95 °C for 3 min followed by 50 cycles at 95 °C for 15 s and 60 °C for 1 min. Amplification reactions were carried out in 384-well plates in a 7900 sequence detector (Perkin-Elmer Applied Biosystems) and analyzed by a sequence detector system (SDS 2.2.1; Applied Biosystems). Each plate included patie nt DNA samples, positive controls (Bisulfite-converted Universal Methylated Human DNAStandards (Zymo Research) in serial dilutions 20ng to 2pg) and molecular grade water was used as a non-template control. The ÃŽ ²-actin gene was used to normalize and act as an internal loading control. The methylation ratio was the ratio of values for the gene-specific PCR products to those of the ACTIN B and then multiplied by 1,000 for more efficient tabulation. Statistical Methods The overall survival (OS) time was defined from the date of initial diagnosis of the disease (surgery) to the time of death or censored at the time last known alive. The recurrence-free survival (RFS) was counted from the date of initial diagnosis of the disease to the time of disease recurrence or censored at the time last known alive and recurrence-free. Probabilities of OS and RFS were estimated using the Kaplan-Meier (KM) method [15] and compared using Log-rank test. Confidence intervals were calculated using the method of Brookmeyer and Crowley[14]. Cox proportional hazards model [16] was used to estimate the association between OS or RFS and MGMT methylation status, treatments and well known prognostic factors. Schoenfeld residuals were used to test the proportionality of factors in Cox proportional hazards models. Radiation status was treated as a stratification factor in the Cox regression model. TMZ has FDA approval for newly diagnosed GBM patients aged between 18-70. Subgro up analyses were performed for patients who were aged over 70. All p values were two-sided. All analyses were performed using the Statistical Analysis System, version 9.2. MGMT was considered as promoter methylated if the methylation ratio was higher than 8, and unmethylated if below 8. RESULTS Patient Population Six hundred patients with newly diagnosed GBM underwent craniotomy between 1997 and 2006, at the Johns Hopkins Hospital. One hundred eighty five patients received Gliadel (30.8%) after tumor resection. Methylation specific PCR was performed in 122 of the 185 patients (66%) because 63 patients did not have sufficient paraffin embedded tumor tissue for MGMT analysis. The characteristics of the patients and type of treatments are shown in Table 2. The clinical course of forty patients who had methylation of MGMT promoter was compared to 82 patients without promoter methylation of MGMT. The similarity of distributions among patients characteristics, and treatments between MGMT methylated and unmethylated is also shown in Table 2. There was a slightly male predominance in both groups. The median age of the MGMT methylated group was 65.5 years compared to 60.5 years in the non-MGMT methylated group (p=0.59). Most of the patients in both groups had KPS score of ≠¤ 80 (p=0.67). Most of the patients in both groups underwent gross total resection (GTR) (85% vs. 74% in the methylated and non-MGMT methylated group, respectively), (p=0.19). Most of the patients in the MGMT methylated and non-MGMT methylated groups received post-operative radiation therapy (RT) (80% and 72% respectively). However, there were 31 patients (25%) without radiation treatment recorded in their medical chart. Only 33% and 29% of MGMT methylated and non-MGMT patients, respectively, were treated with TMZ due to majority of patients was treated prior to 2005 when RT+ TMZ became the stadnadrd of care for the newly diagnosed GBM patients. Overall Survival The Kaplan-Meier estimate of the median OS for the122 patients with newly diagnosed GBM was 13.5 months (95% CI: 11.0, 14.5). Median OS for those with MGMT methylation was 13.9 months (95%CI: 9.5, 17.1) compared to 12.9 months (95%CI: 10.9, 14.5) (p= 0.86) in patients non methylated. Univariate and multivariate association of survival with treatment factor, baseline prognostic factors, and MGMT methylation status are shown in Table 3. There was a 15% reduction in hazard of death (Hazard ratio: 0.85, 95%CI: 0.56-1.31) for patients with MGMT methylated tumor compared to those with MGMT unmethylated tumor after adjusting for age, KPS, extent of resection, TMZ and RT. A subgroup analysis was performed among 35 patients who were 18-70 years old and treated with Gliadel, RT and TMZ ( Gliadel+ Stupp’s regimen) [1]. The median OS was 19.8 months (95% CI, 14.5, 22.2) in this subset of patients. There was no statistically significant difference in OS among these 35 patients with MGMT pr omoter methylation (median OS:20 months,95% CI: 9.2, 37.0), compared to patients without MGMT promoter methylation (median OS: 18.9 months, 95% CI: 11.9, 22.2), (Table 4). Only two out of 30 elderly patients aged above 70 years were treated with TMZ, one was MGMT methylated and another was not. Among these elderly patients, those with MGMT promoter methylation showed a significantly longer median survival of 13.5 months (95% CI, 0.49, 17.1) compared to 7.6 months (95% CI, 2.9, 9.4) when the MGMT promoter was non-methylated (p=0.027). A similar significant difference in median recurrence-free survival was also found in elderly patients where the median survival was 13.1 versus 7.6 months (p=0.01) for MGMT methylated and unmethylated, respectively. The overall median recurrence-free survival was 9.4 months (95%CI: 7.8-10.2) for all patients. There was no difference in RFS between patients 18-70 years old with and without MGMT methylation. DISCUSSION In this study we investigated the significance of MGMT methylation status in a series of 122 patients with newly diagnosed GBM who underwent surgical resection and implantation of Gliadel wafers. The results of our series show a reduction in hazard of death for patients who were MGMT methylated compared to non-methylated. Interestingly, this effect was much more profound in the elderly group of 35 patients who were older than 70 years old when they were diagnosed with GBM. Elderly patients who were MGMT methylated had significantly better OS, compared to non-methylated (13.5 vs. 7.6 months respectively, p=0.027). The methylation of the MGMT promoter region leads to a reduced ability to repair DNA damage induced by alkylating chemotherapeutic agents [7]. Methylation of the MGMT promoter was found to be associated with responsiveness to alkylating chemotherapeutic agents such as temozolomide [6] and BCNU [7], and an increase in OS and progression free survival. The median survival of patients who received the combination of Gliadel, temozolomide and radiation therapy in our cohort ranged between 18.9 to 20 months, six months greater than that for the radiation therapy and temozolomide historic cohort [1] (Figure1). For patients younger than 70 years old, the median survival of the MGMT methylated sub-group was slightly greater that MGMT non-methylated. KPS in a known prognostic factor for patients with brain tumors [8]. Most of the patients in our study cohort had poor KPS of less than 80. Still, our results were in line with the report of Lechapt-Zalcman et al. [9] who assessed the prognostic impact of MGMT promoter methylation in patients with newly diagnosed GBM that received Gliadel in addition to radiation therapy and temozolomide. The OS of their study cohort was 17.5 months. Patients with MGMT methylation had a significantly longer OS of 21.7 months compared with patients without MGMT methylation who had OS of 15.1 months. Two recent phase III clinical trials in the elderly age of patients with malignant astrocytoma, the NOA-08 [10] and Nordic trials [11], demonstrated that temozolomide therapy alone was not inferior to radiotherapy alone, and methylation of the MGMT gene promoter was associated with a benefit from temozolomide. However, there is a concern that combination therapy of radiation therapy and temozolomide may be less active and less well tolerated in the elderly population [12]. European Organization for Research and Treatment of Cancer (EORTC)-26981/National Cancer Institute of Canada (NCIC) CE3 trial have suggested that with increasing age, the relative benefit of addition of temozolomide to radiotherapy decreases and the patients suffer from increased chemotherapy-associated side effect such as neutropenia, lymphocytopenia, thrombocytopenia , raised liver-enzyme concentrations infections and thromboembolic events. As opposed to systemic chemotherapy with its limitations, local delivery of Gliadel wafers may be promising in this subset of patients. Chaichana et al. compared 45 elderly patients who were treated with Gliadel to 88 elderly patients who did not receive Gliadel [13]. The survival for older patients who received Gliadel was significantly longer than for patients who did not receive Gliadel (8.7 months vs. 5.5 months respectively, p=0.007). The median survival of MGMT methylated in elderly patients in the current cohort was doubled. These results may support the use of Gliadel in this sub-population. Limitations There are several limitations to this study. Its retrospective nature carries a potential bias. Moreover, the time period of this study ended in 2006, only one year after temozolomide became the standard of care in the treatment of GBM, thus most of the patients were not treated with the combination of temozolomide and radiation therapy. Furthermore, because this is a tertiary referral center, there is a bulk of patients who were operated in this center, but received further neuro-oncology treatments elsewhere, near their home, and therefore, their complementary oncology treatment is not available. Still, this large and unique cohort of patients with newly diagnosed GBM who were operated in one tertiary center provide novel data that may assist in optimizing and personalizing the treatment for GBM patients.

Saturday, January 18, 2020

Cognitive Biases in Entrepreneurial Strategies

The view of the human as a rational being is nowadays heavily questioned (Simon, 1959), UT in science a lot of models and theories still are based on this assumption. When looking at research on entrepreneurship, we notice that it is considered a relatively new field of study, though practice has shown that entrepreneurial activities have a great influence on the market. Schumacher (1934) already linked entrepreneurial Initiatives of Individuals to the creation and destruction of Industries, as well as to economic development.More research has been conducted about entrepreneurship, which questions the classical picture of the economic man – Homo economics – and he classical concept of rationality. This might be because the entrepreneur himself Is one of the most crucial factors of either the success or failure of an entrepreneurial business. This has caused the entrepreneur to be a hot topic and so a lot of research has been dedicated to the phenomenon. An Shame to (200 0) for example different argues that the underlying factor that causes entrepreneur knowledge. Other research has focused on the traits of entrepreneurs.In general, entrepreneurs are considered overconfident (Cooper et al. , 1988), which is a good thing if you want to start-up a company. Without this trait, start-ups would probably not take place as often as we observe (Goodness & Lecher, 2013). However, research has also showed that this overconfidence is associated with failure (Camera & Lovable, 1999). Nobel (2011) argued that although we know 30 to 40 per cent of entrepreneurial firms fail, many other are bought out or never bring expected return on investment, meaning that the real failure rate can be up to 70 or 80 per cent.Overconfidence is one of the known biases that influence human beings in decision making. There are, however, a lot of more biases which an entrepreneur can encounter. This raises the question of whether being aware example of such of the biases could help the bias, entrepreneur in his activities. If we look at the overconfidence overconfidence can lead to wrong decisions. Awareness thus, could be helpful. On the other hand, if the entrepreneur is aware of this bias he could become too careful in the decision making process. This can result in no action being taken when the ‘moment' arrives.Or it could result in the entrepreneur even deciding not to continue due to the risks being too high. This leads us to the question: 3 The following questions will help us answer the main question by shedding some eight on the biases that are out there: Theory of Bounded Rationality As mentioned in the introduction, we assume Homo economics appears to be perfectly rational and has complete knowledge, while the economic choices one makes are clandestine in the economic sphere without affecting other aspects of the individual such as emotions or being influenced by the environment.This is in line with the neoclassical economic theory that assum es full What is a cognitive bias? Why does this article address cognitive biases? What kind of cognitive biases could an entrepreneur encounter? Theory In this section the previously stated substitutions will be answered based on theory of decision-making, cognitive biases and the application to entrepreneurship. Entrepreneurship We accept the definition of entrepreneurship as suggested by Stevenson and Carillon (1990): ‘Entrepreneurship is about individuals who create opportunities through various modes of organizing, without regard to resources currently controlled. Sevens and Carillon moved away from the view of the traits school' which tried to describe how entrepreneurs differed from other people by control, leadership, or propensity for risk-taking. When studies showed that entrepreneurs are as different from one another as they are from school' non- entrepreneurs, the ‘behavioral rationality. This view has been criticized by Simon (1959) who developed an approach based on bounded rationality and problem solving. Simon stated that the assumption of full rationality is unrealistic.In his view, the rationality of individuals is limited by the information they have, the cognitive limitations of their minds and the finite amount of time they have to make decisions. The theory of bounded rationality states that individuals face uncertainty about the future and costs in acquiring information in the present. What is a cognitive bias? Biases and heuristics (mental shortcuts) are decision rules, cognitive mechanisms, and subjective opinions people use to help them making decisions. This is a deviation of the benchmark Cognitive of biases rational prevent decision-making. Individuals to accurately understand reality and interfere with the ability to be impartial, unprejudiced or objective (Goodness and Lecher, 2013). Taverns and Keenan (1974) state that people rely on ‘heuristic principles which reduce the complex tasks of assessing probabilities and predicting values to simpler Judgmental operations. There are specific and systematic biases that move the Judgment away from the perfect rationality of individuals. Argued that the process of creating a new venture, should be the fundamental part of defining someone as an entrepreneur. (Gideon, 2010).This is why we agree on the definition by Stevenson and Carillon, which also implies we will not discuss entrepreneurial traits in this article. 4 Drawing on aspects of both psychology and economics, the operating assumption of behavioral economics is that cognitive biases often prevent people from making rational decisions, despite their best efforts. Why do we focus on cognitive biases? The general opinion about entrepreneurs is that they are risk takers. However, research showed that if entrepreneurs have to choose, they prefer to take moderate risks instead of taking decisions where there is high risk involved (Keenan and Lovable, 1994).This seems a contradiction, because the decision to become an entrepreneur is statistically a highs decision since over half of new ventures fail. In a study conducted by Cooper and colleagues their (1988), 95 per cent of the The interviewed entrepreneurs venture would did not entrepreneurs were convinced succeed. Where there is a complex interplay between feelings and thoughts which have awoken intense emotions. He concludes deal with that these entrepreneurs frequently situations that are new, unpredictable and complex. What kind of cognitive biases could an entrepreneur encounter?When we look at what kind of biases an entrepreneur can encounter, it needs to be known what kind of biases exist. There are dozens of known biases but not all an entrepreneurs will meet. We would like to discuss the biases that came across the most in research of cognitive threats of entrepreneurs. Optimism bias. The decision to become an entrepreneur is a crucial step that only can be taken if the entrepreneur is feeling optimistic about the chances of success. Because the chance of failure is statistically higher than success, entrepreneurs usually have an optimism bias.As mentioned before, 95 per cent of the entrepreneurs perceive the future of their new venture as being successful, while past studies of business survival suggest poor prospects for long-term survival for most new businesses (Cooper et al. , 1988). The optimism bias makes because entrepreneurs they see perceive less risk, more everything receive the new venture as a risk and their perception, rather than objective reality, explained the decision to start a current or future venture. That is why entrepreneurs do not necessarily have a higher risk propensity than other people (Keenan and Lovable, 1994).They simply perceive existing risks smaller than they are which shows that entrepreneurs are biased. Baron (2004) suggests that entrepreneurs are more often exposed to situations that test the limits of their cognitive capacities than other people. This i ncreases their susceptibility to various forms of bias or error. Baron argued that biases occur more frequently when individuals are confronted with more information than they can process at a given time, they face situations that are new to them and involve high degrees of uncertainty, and optimistically.In ‘The Evolution of Cognitive Bias', (2005) Hasten, Nettle, and Andrews state that where biases exist individuals draw inferences or adopt beliefs where the evidence for doing so in a logically sound manner is either insufficient or absent. In the case of 5 entrepreneurs however, we see that even if logical sound manner is sufficient still an entrepreneur can be biased. In the experiment by Cooper and colleagues (1988) 95 percent of the entrepreneurs was thinking that their venture would be a success, disappear when they knew about the objective chances.Business and Barney (1997) have stated that the optimism bias of an entrepreneur could also influence the stakeholders arou nd them as well. If the stakeholders wait until they attain all additional information, the opportunity they seek to exploit could be gone by the time this data is available. This means that the optimism bias of an entrepreneur can even overrule the rationality of other persons involved. Illusion of control The illusion of control gives the entrepreneur a sense of control that increases the likelihood of them acting on an opportunity, but at the same time it may blind them to genuine risks. Simon et al. 2000) The illusion of control states that decision makers often overestimate the personal control they have over the outcomes. This type of bias influences the ability for decision makers to actually make a decision. This could also be the reason many entrepreneurs fail even though they thought they had made a right decision. Belief in the Law of Small Numbers The belief in the law of small numbers is the use small off limited sample of to draw rim are conclusions. The bias makes peo ple believe samples information representative of the entire population from Overconfidence bias.Overconfidence refers to an unwarranted, high level of confidence (Forester and Scratchy, 2007). It is interesting that overconfidence can only be determined in retrospect, after an evaluation of knowledge, predictions and outcomes. Therefore, it will be difficult to notice beforehand if an entrepreneur is dealing with an overconfidence bias. Because of overconfidence, people do not take into account other factors and information that they need for decision-making. Goodness and Lecher optimism (2013), bias and argued distrust. Hat They the overconfidence bias is influenced by both the see overconfidence as a central theme in the failure of entrepreneurial firms with its effects magnified in combination with other cognitive biases. Which they are drawn (Simon et al, 2000). Simon and Houghton (2002) argued that belief in the law of small numbers may explain why entrepreneurs often overesti mate demand. The success of a small number of people in their own environment can make entrepreneurs think that they will also be successful, while the objective probability of success may be very low.Business and Barney (1997) mint out that entrepreneurs often use biased samples from a small number of friends or potential customers. Decision-makers versus Entrepreneurs Business and Barney mentioned that entrepreneurs are influenced by the sorts of cognitive biases that we all as individuals encounter (1997). However, they found that the extent to which people deviate from rational thinking may not be constant and that different individuals may utilize biases and heuristics to different degrees.They argued, and Baron (2004) agrees, that entrepreneurs in general are more susceptible to the use of biases and heuristics in decision-making. For entrepreneurs, the level of uncertainty in making decisions is higher than for general decision-makers (Humpback and Cozier, 1985; Covina and Sl iven, 1989). Also, general managers can approximate the rational ideal more closely because they usually have access to historical trends and past performance, while entrepreneurs do not. Several studies (Covina and Sliven, 1991; Garner et al. 992; Miller and Ferries, 1984) have shown that the context faced in decommissioning by entrepreneurs tends to be more complex than the context faced by managers. Pitfalls, biases and heuristics are likely to have more utility in hose highly complex decision settings faced by entrepreneurs, compared to the less complex context that managers face (Business and Barney, 1997). We find that entrepreneurs in general encounter, and until now no attempt has been done in making such a list. Simon et al. (2000) did make a selection in their research towards risk perception and the start of a new venture.They selected three biases that may lower risk perception when starting a new venture. Their research focused on the overconfidence bias, the illusion o f control and the belief in small numbers (see table 3). In their research optimism did not have a significant relationship with the decision to start a new venture, therefore they left this bias out of the model. Striking is that they left optimism out of their model, because they found a lack of significant relationship between optimism and the decision to start a venture.They mentioned however that other studies did encounter optimism affecting both cognition and behavior and explain that their outcome may have occurred because their survey measured optimism in a specific context. Further research on at least the optimism bias therefore is necessary. What influence can biases have on the success or failure of an entrepreneurial firm? Biases can have great impact on the success or failure of a company. Goodness and Lecher (2013) argued that their research shows that overconfidence can lead to disastrous effects in the entrepreneurial domain.In fact, they even found a strong relati onship between overconfidence and company failure, especially if overconfidence was linked with other biases. Also they found that optimism bias has a negative effect on firm survival, strengthening arguments on low risk perception and resultant propensity to fail. However optimism bias also acted positively on opportunity orientation. This is an important encounter more biases than other types of decision-makers, but no specific research has been done on framing the most common biases faced by entrepreneurs.In the field of strategic decision-making however, Hogwash described the 29 most common separate biases (1980). The ones that he considered most likely to affect strategic decisions are listed in table 1. An overview like this is missing in the field of entrepreneurship. One reason for this might be that most entrepreneurship common biases is hard to frame. Previous research did not mention a list of the that 7 finding, as one of the important aspects of entrepreneurship is find ing opportunities. Effective decision-making by entrepreneurs with respect to actions involving risk could play an important role in the success of new ventures.Empirical findings in literature about entrepreneurship offer support for the possibility that successful entrepreneurs are more effective at this task. Simon et al. (2000) found that effectiveness at decision making is an important factor in the performance of new ventures. Lovable and Keenan (1993) prescribed corrective measures to overcome the biases and achieve optimal behavior in every situation. Also Russo and Shoemaker (1989) reasoned that decision biases can be corrected through training.They have indicated that every decision-maker must, consciously or unconsciously, go through each phase of the decision-making process. They have stated ten most common barriers that entrepreneurs encounter in making good decisions. These barriers show resemblance with the biases described by Hogwash (1980). The availability bias, â €˜Judgments of probability of clearheadedly events are distorted', can be linked to the trusting shortsighted the most shortcuts, readily ‘relying or inappropriately on rules of thumb such as information anchoring too much on invention facts'.Both of them trust the most readily available information and thus the Judgment of probability may be distorted. Conservatism, which is the failure to sufficiently revise forecasts based on new information, can be linked to fooling ourselves about feedback, since in both cases the feedback will not be taken into account when forecasting new decisions, which can also emerge from being overconfident in making a Judgment. Russo and Shoemaker (1989) indicated that good decision-making can be broken down into four main elements: (1) framing; (2) gathering intelligence; (3) coming to a conclusion; (4) learning from feedback.Entrepreneurs have to keep track of what they expected to happen while guarding and against Lecher self-serving (2013) also explanations. Goodness agreed with the effectiveness of training on biases. They stated that for example the training of unrealistic optimists should stimulate the motivation to manage finances, to take advice, not to leave matters up to chance, and to understand the value of healthy distrust in oneself and others in non-routine situations.However, they also warned that training programs for entrepreneurs are not always a good idea. If it was not for the cognitive biases, start-ups would not occur as often as we observe now. Their advice for entrepreneurs is to balance the organization with people that are aware of these biases and can correct the entrepreneur where necessary. As well, Taverns and Keenan (1974) do not consider the biases as something that always should be eliminated.They argued that under conditions of environmental uncertainty and complexity, biases and heuristics sometimes also can be an effective and efficient guide to decision-making, simply because in such settings comprehensive and cautious decommissioning is not always possible. They state that biases and heuristics may even provide an effective way to Training When a bias causes harm, it is of critical importance that it can be addressed properly. Errors in decision-making can be extremely costs at not only the personal but also at the professional and societal level.As this article indicates, there does not seem to be an easy fix. Building further upon his previous work, Fishhook (1982) reviewed four strategies for reducing bias: (1) warning subjects about the potential for bias, (2) describing the likely direction of bias, (3) illustrating bias to the subject, and (4) providing extended training, feedback, coaching and other interventions. Fishhook concluded that these first three strategies yielded limited success, and that ‘even intensive, personalized feedback and training produced only moderate improvements in decision making. This model, derived from Wilson and Breake r (1994), shows how Judgmental biases are created and how they can be reduced. Awareness should first be created, there must be motivation to correct this bias and the direction and magnitude of the bias should be understood. As a final step, the bias should be removed or countered. But what is interesting is to see which techniques can be used to mitigate the bias of concern. We believe this can be done by applying a counter bias or by structuring the decision-making process.If decision makers rely less on intuition and emotion when making a decision, and more on deliberate and structured thinking processes, a decision can be made which approximates rationality. Analysis A list of the most common biases among decision-makers (note this it is not a list of the most common among entrepreneurs) have been framed earlier in this paper by Hogwash (1980). It is known that entrepreneurs are more susceptible to the effects of biases, but it is doubtful whether the most important biases for decision-makers are also the most important ones for entrepreneurs.The optimism bias and overconfidence decision-makers, bias do not appear on in the Hogwash's list of most common biases for while research cognitive biases of entrepreneurs mentions them often. The problem with making an analysis on the cognitive biases that entrepreneurs encounter is that there is no such a list of most common biases among entrepreneurs. Earlier in this paper, we accepted the definition by Stevenson and is Carillon several to (1990) modes that of entrepreneurship opportunities organizing without about creating resources through rage rd currently controlled.This made us not look at the traits of an entrepreneur, but at the processes of decision-making and biases that can occur. There are biases that every person encounters, but there are certain biases that have a more effect on decision-making but also have to be aware of different sorts of biases that can influence their perception of the world. Th is can be of great influence on the future of their new ventures. As Abide (1994) argued, there are three critical elements of successful entrepreneurial approaches.Entrepreneurs 9 have to screen opportunities quickly to weed out unpromising ventures, they have to analyze ideas in which they focus on new important issues and they have to integrate taking action and analysis. His most important conclusion is that entrepreneurs must reflect on the adequacy of their ideas and their capacities to execute them. This comes back to what we are addressing in this article. Can entrepreneurs be aware of adequacy of their ideas? And is it recommendable to create this awareness among entrepreneurs?To be able to have a better perception of the world and thus be better capable of reflecting and making decisions, biases are of great importance. Hen reflecting on the environment of the new venture and when making decisions based upon those reflections. Training programs to become aware of bias do e xist. Russo and Shoemaker (1989) proposed a training system in which good decision- making can be broken down into four main elements. In each element the person involved is encouraged to take the different barriers (table 2) into account so that he or she is guarded against silvering explanations.However, Goodness and Lecher (2013) argued that when entrepreneur are aware of biases, probably less start-ups will be realized. They advise that not the entrepreneurs will follow a raining program, biases. But rather people around the entrepreneur should be aware of existing Conclusion Although there are frameworks of individual cognitive biases in the literature of decision making, like the barriers by Hogwash (1980), there is no clear framework which cognitive biases entrepreneurs commonly encounter and how and if the effects of these biases should be reduced.The biases studied showed however that they can have big influence on the success or failure of a new venture. Goodness and Leche r (2013) found a strong relationship between overconfidence and company failure. Also positive biases strengthen low risk reception and increased the chance of failure. On the other hand, a positive bias in the startup phase of the company could be of great help because it strengthens the entrepreneur in motivation and opportunity finding.If entrepreneurs are aware of their biases, they could take this knowledge into consideration Taverns and Keenan (1974) pointed at the fact that not always should be eliminated. Under conditions of environmental uncertainty and in complexity, biases and simply heuristics because sometimes also can be effective and efficient decision-making, comprehensive and cautious decision-making is not always possible. Being aware of cognitive biases contributes towards obtaining optimal behavior in every situation.However, when we want to answer the question if awareness helps entrepreneurial firms perform better we would like to advise to also create awarenes s among the people around the entrepreneur and not the entrepreneur himself. The bias of an entrepreneur can be crucial in the start-up of a company and the motivation of other people. However, when a bias is harmful people around him can undertake action to 10 eliminate this bias and therefore reduce the chance of a company's failure. As a radical note we would like to mention that research on biases that an entrepreneur can encounter still has not been done.